Abstract
Analyze patterns of association between diagnoses related to domestic violence in hospital admissions and identify clinical-demographic profiles using unsupervised machine learning. Data from the SUS Hospital Information System between 2008 and 2023 were used, covering 90,798 hospitalizations of women aged 20 to 59 years with ICD-10 codes related to violence. Frameworks for data preparation were applied, as well as algorithms for identifying association rules between diagnoses and topic modeling. The hospitalization rate stabilized after 2012, with an average between 2.6 and 3.2 per 100,000 women. States such as São Paulo, Bahia, and Minas Gerais accounted for 46% of absolute cases; Rio Grande do Norte and Pará presented the highest proportional rates. The algorithm identified significant rules between types of injury and mechanisms of aggression. Latent Dirichlet Allocation modeling revealed nine distinct profiles, highlighting young women undergoing emergency surgeries due to polytrauma. The use of machine learning identified relevant clinical-epidemiological patterns to support prediction and surveillance strategies in Primary Care, contributing to addressing gender-based violence.
Key words:
Violence Against Women; Hospital Information Systems; Machine Learning; Artificial Intelligence
Resumo
Analisar padrões de associação entre diagnósticos relacionados à violência doméstica em internações hospitalares e identificar perfis clínico-demográficos por aprendizado de máquina não supervisionado. Utilizaram-se dados do Sistema de Informações Hospitalares do SUS entre 2008 e 2023, abrangendo 90.798 internações de mulheres de 20 a 59 anos com códigos CID-10 relacionados à violência. Aplicaram-se frameworks para preparação dos dados, e algoritmos para identificação de regras de associação entre diagnósticos e modelagem de tópicos. A taxa de internações estabilizou após 2012, com média entre 2,6 e 3,2 por 100.000 mulheres. Estados como São Paulo, Bahia e Minas Gerais concentraram 46% dos casos absolutos; Rio Grande do Norte e Pará apresentaram as maiores taxas proporcionais. O algoritmo identificou regras significativas entre tipos de lesão e mecanismos de agressão. A modelagem Latent Dirichlet Allocation revelou nove perfis distintos, com destaque para mulheres jovens submetidas a cirurgias de urgência por politraumatismos. O uso de aprendizado de máquina identificou padrões clínico-epidemiológicos relevantes para subsidiar estratégias de predição e vigilância na Atenção Primária, contribuindo para o enfrentamento da violência de gênero.
Palavras-chave:
Violência contra a Mulher; Sistemas de Informação Hospitalar; Aprendizado de Máquina; Inteligência Artificial
Resumen
Analizar patrones de asociación entre diagnósticos relacionados con la violencia doméstica en hospitalizaciones e identificar perfiles clínico-demográficos mediante aprendizaje automático no supervisado. Se utilizaron datos del Sistema de Información Hospitalaria del SUS entre 2008 y 2023, abarcando 90.798 hospitalizaciones de mujeres de 20 a 59 años con códigos CIE-10 relacionados con la violencia. Se aplicaron marcos para la preparación de los datos, así como algoritmos para la identificación de reglas de asociación entre diagnósticos y el modelado de temas. La tasa de hospitalizaciones se estabilizó después de 2012, con un promedio entre 2,6 y 3,2 por 100.000 mujeres. Estados como São Paulo, Bahía y Minas Gerais concentraron el 46% de los casos absolutos; Río Grande do Norte y Pará presentaron las tasas proporcionales más altas. El algoritmo identificó reglas significativas entre tipos de lesión y mecanismos de agresión. El modelado Latent Dirichlet Allocation reveló nueve perfiles distintos, destacándose mujeres jóvenes sometidas a cirugías de urgencia por politraumatismos. El uso de aprendizaje automático identificó patrones clínico-epidemiológicos relevantes para sustentar estrategias de predicción y vigilancia en la Atención Primaria, contribuyendo al enfrentamiento de la violencia de género.
Palabras clave:
Violencia contra la Mujer; Sistemas de Información Hospitalaria; Aprendizaje Automático; Inteligencia Artificial
Introduction
Violence against women is a serious public health problem in Brazil, leading to high rates of morbidity, mortality, and psychological distress among women1. Beyond its physical and emotional consequences, gender-based violence places a substantial burden on the health system. Primary Health Care (PHC) is the main gateway to the Brazilian Unified Health System (SUS). It plays a strategic role in early detection, qualified reception, and coordination with social protection networks2.
In Brazil, the steady increase in reports of violence against women over recent decades underscores the magnitude and urgency of this public health issue3. Despite expanded policies and protection networks, regional inequalities, structural barriers, and limited access to health and social services persist, compromising prevention and early detection4.
Analyzing the most severe cases, such as those resulting in hospitalizations, is especially relevant for understanding complex clinical patterns. Previous Brazilian studies have examined individual or sociodemographic characteristics1,5, yet integrated analyses of diagnoses and clinical features of hospitalizations are limited, hindering identification of severity profiles and care needs.
International experiences6,7 highlight the role of Digital Health, including Data Science, in strengthening surveillance, integrating information, and identifying vulnerable populations. Guidelines such as the Fit for the Future plan6 and the World Health Organization (WHO) Digital Transformation Handbook for Primary Health Care7 point to the adoption of predictive, responsive, and population-centered care models. Unsupervised machine learning techniques have emerged as promising tools for revealing hidden patterns in large datasets8,9.
Accordingly, this study aimed to analyze, using unsupervised machine learning techniques, patterns of association among diagnoses related to violence against women in hospitalizations recorded in the SUS Hospital Information System (SIH-SUS), and to identify the clinical-demographic profiles of these admissions, thereby providing evidence to inform future surveillance, prevention, and comprehensive care strategies.
Methods
We conducted a retrospective, analytical, and observational study using secondary SIH-SUS data from 2008 to 2023, covering the entire Brazilian territory. The study population comprised women aged 20-59 years admitted to SUS hospitals with domestic violence-related diagnoses. To explore data patterns, we applied unsupervised machine learning techniques, including topic modeling and association rules. The Unifesp Research Ethics Committee approved the study under Opinion No. 00263/2023.
The study was conducted at the Department of Health Informatics of the São Paulo School of Medicine, Federal University of São Paulo, in partnership with the São Paulo Association for the Development of Medicine, from April to July 2025. All data used were public, anonymized, and handled in accordance with current ethical and regulatory principles, including the Brazilian General Personal Data Protection Law (Law No. 13,709/2018) and National Health Council Resolution No. 510/2016.
We employed public secondary databases, including SIH-SUS10 for information on SUS hospitalizations, ICD-1011 for diagnostic classification, SIGTAP12 for descriptions of the procedures performed, and population data from the Brazilian Institute of Geography and Statistics (IBGE)13. Based on these sources, the hospitalization rate per 100,000 inhabitants was calculated and stratified by federative unit (state) and year, using the number of hospitalizations as the numerator and the female population aged 20-59 years as the denominator, multiplied by 100,000.
The inclusion criteria comprised hospitalizations of adult women aged 20-59 years, excluding children, adolescents, and older women, as per the categorization proposed in the Ministry of Health’s Health Surveillance Guide14. Records with diagnoses related to domestic violence were selected, including ICD-10 codes for assaults (X85-X99, Y00-Y09), maltreatment syndromes (T74), sequelae of assault (Y87.1), and examination and observation following alleged rape and seduction (Z04.4). To ensure comprehensive capture of diagnoses, we considered the primary diagnosis, secondary diagnosis, and additional diagnosis fields available in the SIH-SUS database. The final sample comprised 90,798 hospitalizations.
To guide planning and the data preparation process in health, we applied the HRSP-AI15 and HealthDataPrep9 frameworks. The steps included: 1) De-identification: removal of identifying fields such as the Hospitalization Authorization (AIH), taxpayer identification numbers for individuals and companies; 2) Cleaning: exclusion of variables with only one value or variance below 1%, such as schooling level, occupation, social security status, among others; 3) Integration: combining SIH-SUS, population (IBGE), procedure table (SIGTAP), and ICD data; 4) Transformation: conversion to categorical attribute-value format (state, gender, ethnicity/skin color, bed type, progress, death, and ICU) and discretization of the continuous age variable into intervals (age groups); and 5) Attribute selection: state, age group, ethnicity/skin color, bed type, procedure, progress, death, ICU, hospitalization type, and diagnoses (Figure 1).
Use of the HRSP-AI15 framework to guide the AI project process and the HealthDataPrep framework for preparing unsupervised data.
For association rule analysis, we employed the Apriori algorithm to identify patterns among diagnoses16. The following criteria were established: Support≥1%, Confidence≥30%, and Lift≥1.5. These values were adjusted by size of the database and were based on previous studies that applied the Apriori algorithm to health datasets17,18. The metrics used were Support, defined as the frequency of an item combination vis-à-vis the total dataset; Confidence, defined as the probability of occurrence of the consequent diagnosis given the antecedent; and Lift, defined as the strength of dependency between diagnoses (>1 indicates positive dependence)19,20.
For topic modeling, we applied the LDA algorithm8,21, and the data were structured in attribute-value format. In addition, we used the Perplexity metric8,22 to determine the optimal number of topics, testing models with 2 to 15 topics. This approach was grounded in previous studies using health data23,24. The final number of nine topics was selected based on stabilization of perplexity. The source code used for all steps of data preparation and application of the Apriori and LDA algorithms was made publicly available at https://doi.org/10.5281/zenodo.17872231.
Results
The results obtained from the analysis of SIH-SUS data using unsupervised machine learning techniques revealed relevant patterns of hospitalizations for violence against women in Brazil from 2008 to 2023. This section is organized into three parts: (1) General characteristics of hospitalizations; (2) Identification of association rules among diagnoses using the Apriori algorithm; and (3) Topic modeling with the LDA algorithm to describe latent profiles of hospitalizations. Each approach highlighted different dimensions of gender-based violence in the hospital context, with implications for health surveillance, public policy formulation, and clinical practices sensitive to the complexity of these cases.
General characteristics of hospitalizations
A total of 828,264 (0.43%) of the 193,455,105 hospitalizations recorded in SUS from 2008 to 2023 corresponded to violence-related codes, of which 144,140 (17.4%) involved women. After applying the age criteria, 90,798 cases of women aged 20-59 years were retained.
The hospitalization rate for violence against women stabilized after 2012, ranging from 2.6 to 3.2 per 100,000 inhabitants. In absolute numbers, São Paulo (17,963 cases), Bahia (13,893), and Minas Gerais (10,184) accounted for 46% of the national total. When population rates were considered, Rio Grande do Norte had the highest mean rate (17.49/100,000 inhabitants), followed by Para (6.49/100,000).
Age distribution showed greater concentration in the 20-30-year age group, with a progressive decline with age. Regarding ethnicity/skin color, 35.57% self-identified as brown, 20.49% as white, and 38.29% had no information recorded. Most hospitalizations occurred as urgent care (81.87%) and in surgical beds (67.17%) (Table 1).
Association rules among diagnoses
The Apriori algorithm identified nine significant association rules according to the established criteria. The rule with the highest confidence linked injury of muscle and tendon at wrist and hand level (S66) with assault by sharp object (X99), with a support of 1.73%, Confidence of 69.5%, and Lift of 3.14 (Chart 1). Other relevant associations included:
-
Fracture of skull and facial bones (S02) - Assault by physical force (Y04): Confidence 61.05%, Lift 2.99.
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Open wound of breast (S21) - Assault by sharp object (X99): Confidence 59.01%, Lift 2.67.
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Injury of other and unspecified intrathoracic organs (S27) - Assault by sharp object (X99): Confidence 57.28%, Lift 2.59.
The results revealed consistent patterns between specific types of injuries and assault mechanisms, suggesting correlations between the instruments used and the resulting injuries.
Profiles of hospitalizations based on topic modeling
Perplexity analysis indicated that nine was the optimal number of topics, with substantial change up to that point and variations below 1% in subsequent values, suggesting relative stabilization (Figure 2). Each identified topic corresponded to a recurrent profile of hospital care related to violence against women, characterized by specific combinations of the most frequent attribute-value pairs. The nine identified profiles showed distinct distributions (Chart 2):
(a) Analysis of the Perplexity metric for Different Numbers of Topics; (b) Distribution of topics for hospitalizations due to violence against women.
Topic 7 (17.2% of cases): Young women (20-29 years) receiving urgent surgical care for multiple trauma or tube thoracostomy with pleural drainage, discharged with improvement. Brown women predominated, with diagnoses of assault by sharp object (X99) or injury of other and unspecified intrathoracic organs (S27).
Topic 6 (13.5%): Women hospitalized in Sao Paulo and Minas Gerais, in clinical beds, admitted as urgent care, undergoing procedures related to injuries of unspecified location, with diagnoses of assault by physical force (Y04) or open wounds involving multiple body regions (T01).
Topic 3 (10.8%): Older women (40-59 years), predominantly white, residing in São Paulo and Santa Catarina, admitted to surgical beds after assault by bodily force (Y04) or blunt object (Y00).
Topic 5 (5.5%): Mixed-race women from São Paulo and Ceará, victims of assault by rifle, shotgun and larger firearm discharge (X94) or exposure to the toxic effect of other and unspecified substances (T65), undergoing treatment for poisoning or emergency surgical procedures, with ICU admission and death as the outcome.
The remaining topics represented other profiles with diverse geographic, age-related, and clinical characteristics, evidencing heterogeneous violence against women cases within the hospital system.
Discussion
This study conducted a comprehensive analysis of hospitalizations for violence against women in Brazil from 2008 to 2023 using unsupervised machine learning techniques. The findings reveal patterns across three main dimensions: the general characteristics of hospitalizations, including age distribution, ethnicity/skin color, bed type, and regional patterns; patterns of association among diagnoses; and hospitalization profiles. This approach lead us to understand the heterogeneous cases, identify risk groups, and inform public policies, health service planning, and prevention strategies, with particular emphasis on PHC.
The stabilization of hospitalization rates after 2012 may be interpreted as reflecting regulatory advances, such as the Maria da Penha Law (Law 11.340/2006), and the expanded services within the Network of Care for Women in Situations of Violence, especially referral centers and hospital services for sexual violence victims. Nevertheless, studies indicate that a substantial proportion of violence against women remains invisible within the health system because of underreporting, inadequate labeling of SIH-SUS diagnostic codes, or the redirection of victims that do not require hospitalization to emergency and urgent care services25,26.
The regional disparities observed, especially in Rio Grande do Norte and Pará, suggest a complex interaction among the prevalence of violence, service coverage, reporting culture, and access to care. Recent research on the geographic distribution of interpersonal violence in Brazil reinforces the existence of ‘high-incidence pockets’ associated with social vulnerability, weak protection networks, and impunity of perpetrators27-29.
The association rules identified by the Apriori algorithm are particularly relevant from a clinical-forensic perspective. The strong association between wrist/hand trauma and assault by sharp object (Confidence 69.5%; Lift 3.14) may reflect instinctive defensive movements during the attack, as also described in forensic medicine studies30. Similarly, the correlation between craniofacial fractures and assault by physical force (Lift 2.99) reinforces recognized patterns of direct and repeated assault, often associated with severe domestic violence situations31.
LDA modeling identified nine latent hospitalization profiles, revealing case heterogeneity and highlighting the need for differentiated care approaches. The most prevalent profile, involving young women with multiple trauma resulting from assaults with sharp objects, raises concerns about the severity of violent episodes and their physical and emotional repercussions. Qualitative studies have shown that young women tend to be more reluctant to seek formal help, which may delay preventive interventions and deteriorate clinical outcomes32,33.
Based on analysis of these profiles, it becomes possible to propose stratification of the risk of recurrence, clinical deterioration, and social vulnerability. Initiatives such as the implementation of hospital-based centers for comprehensive care for women in situations of violence and active notification and sentinel surveillance protocols may benefit from these findings, improving coordination between epidemiological surveillance, hospital care, and social protection networks34,35.
International studies36,37 have showed the potential of machine learning techniques to identify hidden patterns of gender-based violence and predict risk, as evidenced in analyses using large hospital or public health datasets combined with association and clustering algorithms36,37. Such experiences reinforce the importance of investments in data infrastructure and interoperability within health systems, elements that remain fragile in the Brazilian context38,39.
In this regard, WHO recommendations7 for digital transformation in Health, especially in the field of Data Science, emphasize that this change transcend the mere digitization of records and involve systemic reorganization of information flows with a user-centered focus. One of the proposals in the document prioritizes creating person-centered point-of-service systems and incorporating functionalities for clinical decision support, prediction, and automated surveillance. The application of algorithms to identify patterns of hospital violence, as performed in this study, is aligned with the WHO proposal7 to use technologies to recognize vulnerable populations, identify risks, and promote personalized, intersectoral responses in Health.
In addition, the WHO7 document recommends that, to ensure the effectiveness of these tools, it is essential to map work processes and align functional requirements with local realities, thereby ensuring that digital systems support both health professionals and managers in decision-making. The present study provides knowledge on clinical-epidemiological profiles, which may inform future discussions on improving information systems and decision-support tools.
Despite the robust database and the methodology applied, this study has limitations. Temporal trends and regional differences may reflect changes in recordkeeping, access, and service availability rather than actual variations in violence. Underreporting and inadequate recording of diagnostic codes may compromise internal validity. Moreover, the study includes only hospitalizations and does not encompass visits to emergency care, primary care, or cases that never reach the health system, which limits external validity and prevents a broader assessment of the magnitude of this event.
In conclusion, this study characterized hospitalizations for violence against women in Brazil from 2008 to 2023 and identified patterns of association among diagnoses and clinical-demographic profiles using unsupervised techniques. The results reveal that hospitalizations are concentrated mainly among young, brown women treated on an urgent care basis and often undergoing surgical procedures, with particular emphasis on the strong association between sharp object injuries and multiple trauma. The heterogeneous identified profiles demonstrate that violence produces distinct clinical outcomes, suggesting differentiated care needs and groups with greater vulnerability.
The findings of this study align with national40,41 and international6,7,42 frameworks that recognize violence against women as a complex and multifactorial public health problem. By identifying and organizing little-explored clinical-epidemiological patterns, the present study fills gaps in the literature and provides relevant conceptual support for future discussions on improving surveillance, improving databases, and developing analytical tools in Health.
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The data sources adopted in the research are indicated in the article’s body.



Source: Shimaoka et al.
Source: Authors, 2025.