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Mohan S, et al28 2021 LoE:6 MR: Level A |
- Explore attitudes towards COVID-19 vaccination between women in the perinatal period. - Sample of 341 pregnant and breastfeeding women. |
The distrust of future vaccine problems (70.6%) was a main reason for vaccination hesitation. Factors that would increase confidence in accepting the vaccine were reading about efficacy (33.8%) or positive feedback from family or friends (8.1%). |
| Gencer H, et al45 2021 LoE:6 MR: Level A |
- Determine the opinions of pregnant women about vaccines during pregnancy and childhood and the effect of COVID-19 pandemic on these opinions. - Sample of 152 pregnant women. |
The reasons for vaccination hesitation were listening or reading negative media news (21.7%) and believing that vaccines were not safe or were concerned about side effects (21.7%). |
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Goncu Ayhan S, et al51 2021 LoE:6 MR: Level A |
- Define COVID-19 vaccine acceptance and hesitancy status in a sample of pregnant women in Ankara, Turkey. - Sample of 300 pregnant women. |
63% of pregnant women would refuse the vaccine COVID-19 vaccine even if recommended. Of these, 65.6% declared concern about lack of data on vaccine safety in the pregnant population, and 41.7%, the possibility of harm to the fetus. |
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Stuckelberger S, et al30 2021 LoE:6 MR: Level A |
- Investigate the COVID-19 vaccine availability among pregnant and breastfeeding Swiss women if the vaccine was available as well as the factors that contributed to its acceptance or hesitation. - Sample of 1551 Swiss women (515 pregnant and 1,036 breastfeeding up to 90 days). |
29.7% of pregnant women and 38.6% breastfeeding women were willing to be vaccinated against SARS-CoV-2. Among participants, 10.5% mentioned fear of potential consequences for the fetus/baby. Women in the third trimester of pregnancy who had received influenza vaccination in the previous year were more likely to receive the vaccine. |
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Tao L, et al53 2021 LoE:6 MR: Level A |
- Explore COVID-19 vaccine acceptance and factors related to vaccine acceptance based on the health belief model. - Sample of 1,392 pregnant women. |
Among the 315 pregnant women who answered “no” or “not sure” of their intention to be vaccinated with a COVID-19 vaccine, 54% refused any vaccination during pregnancy due to concern about side effects; 47.0% were concerned about safety; and 44.1% were concerned about vaccine efficacy. |
| Im JH, et al48 2020 LoE:6 MR: Level A |
- Assess changes in influenza vaccination coverage rates and the related factors that influence them in pregnant women. - Sample of 550 pregnant women. |
The common reasons for receiving the vaccine were preventing the flu (49.7%) and ensuring fetal health (46.3%). The most common reason for non-vaccination was lack of sufficient information about vaccination (36.9%). |
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Bettinger JA, et al39 2016 LoE:6 MR: Level A |
- Investigate pregnant women’s and new mothers’ attitudes and behaviors in relation to seasonal and pandemic influenza vaccination. - Sample of 26 pregnant women and eight postpartum women in the focus group (FG); of these, 22 composed the online survey. |
67.6% of FG participants agreed “somewhat” about vaccine safety during pregnancy and, for most of the, the vaccine’s unknown risks do not outweigh the benefits and were concerned about adverse effects of vaccination. In the online survey, 42% of unvaccinated women did not feel informed enough to make the decision to receive the vaccine; 42% were concerned about safety; and 50% did not discuss vaccination with their health professional. |
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Jung EJ, et al29 2016 LoE:6 MR: Level A |
- Assess coverage rate and perceptions of Korean women of reproductive age about influenza vaccine during pregnancy and conduct a virtual intervention to increase their intention to receive vaccination. - Sample of 500 pregnant women and 500 women of reproductive age. |
Among 764 participants, 62.7% did not receive the vaccine during pregnancy and the reasons for not vaccinating were concerns about harmful effects on the fetus (29.6%) and lack of vaccine recommendation by health professionals (12.9%). Of those who received the vaccine, the reasons for vaccination were perceived risk of influenza infection in babies (22.8%), health professionals’ recommendation (26.7%) and belief in vaccine efficacy (15.8%). |
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Mccarthy EA, et al38 2015 LoE:6 MR: Level A |
- Review facilitating and impeding factors in promoting influenza vaccination during pregnancy to inform future lay and professional educational efforts. - Final sample of 1,086 postpartum women. |
65.0% of participants who remembered vaccination being discussed or recommended by a health professional were subsequently vaccinated. The main reason for vaccinating was the desire to protect the baby, which increased from 66.7% in 2010 to 89.2% in 2014, while 47.1% chose not to vaccinate during pregnancy because they do not usually be vaccinated during pregnancy. |
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Halperin BA, et al49. 2014 LoE:6 MR: Level A |
- Explore and compare pregnant women’s pre- and post-pandemic knowledge, attitudes, beliefs and intended behaviors regarding influenza vaccination (seasonal and/or pandemic) during pregnancy in order to determine the main factors influencing their decision to comply with the influenza vaccine recommendations. - Sample of 662 pregnant women in the pre-pandemic period (2005-2006) and 159 in the post-pandemic period (2011). |
The reasons for seasonal flu vaccination were protection against the disease for themselves and their family (44% pre- and 45% post-pandemic) and health professionals’ recommendation (19% pre and 38% post), reasons for vaccination H1N1 (48% and 20%, respectively). Reasons for not vaccinating against seasonal flu were that they did not need to receive immunization (36% pre and 70% post) and concern about side effects (5% and 26%); reasons also cited by women who did not receive the vaccine against the H1N1 pandemic (26% and 14%, respectively). |
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Lohiniva AL, et al34 2014 LoE:6 MR: Level A |
- Describe pregnant women’s perceptions related to H1N1 influenza, to identify the factors that encourage or discourage them to take the A(H1N1) monovalent vaccine pdm09 during the response to the pandemic (2009-2010), and the sources of information that influenced their process of decision-making. - Sample of 123 pregnant women. |
Women feared that the vaccine could negatively affect their health and that of their babies, and speech analysis identified the interference of the social network in the decision-making to receive the vaccine: discussions with health professionals were a positive factor for the decision-making for vaccination, while rumor-based discussions about complications and side effects with neighbors and friends often fuel the decision not to vaccinate. |
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Ahluwalia IB, et al37 2014 LoE:6 MR: Level A |
- Examine disparities in vaccination coverage among women who gave birth during the 2009-2010 influenza season, when two separate influenza vaccinations were recommended. - Sample of postpartum and breastfeeding women, 27.153 for seasonal influenza and 27.372 for H1N1. |
Reasons cited for not receiving vaccination include: lack of recommendation by health care provider about a flu shot during pregnancy; concern about vaccine side effects; concern of harm to the fetus; habit of not getting the flu shot. |
| Kfouri RA, Richtmann R46 2013 LoE:6 MR: Level B |
- Describe the vaccination coverage of pregnant women for influenza and factors associated with vaccine refusal or acceptance. - Sample of 300 postpartum women. |
95.7% received the vaccine against influenza during pregnancy and, of these, 73.2% knew that the vaccine would protect their child. Among those who did not receive it, all were unaware of the fact that the vaccine would protect the baby, and 69.2% would have been vaccinated if they had been informed of neonatal protection. |
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Tarrant M, et al41 2013 LoE:6 MR: Level A |
- Examine factors associated with the adoption of the 2009 influenza A/H1N1 vaccine among pregnant women in Hong Kong. - Sample of 549 postpartum women. |
91.1% did not receive any of the influenza A (H1N1) and/or seasonal vaccines during pregnancy, and the reason cited was the fear that the vaccine would cause side effects to them or their fetus (69.7% and 75.7%, respectively), and reported that vaccination should be avoided during pregnancy (78.8%). |
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Kouassi DP, et al52 2012 LoE:6 MR: Level A |
- Assess awareness of the pandemic and A(H1N1) pdm09 vaccine awareness and acceptance in February 2010, prior to the local availability of the vaccine. - Sample of 411 pregnant women. |
Of the 80 women who said they would not accept being vaccinated, 45% reported lack of information about the vaccine as the reason for not vaccinating. Women who are aware of the pandemic and believe they are susceptible to H1N1 flu were more likely to accept vaccination (75.4%). |
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Honarvar B, et al32 2012 LoE:6 MR: Level A |
- Determine the acceptance rate of influenza vaccination, including the 2009 pandemic influenza H1N1 and seasonal influenza vaccination, and the reasons for acceptance or rejection among pregnant women. - Sample of 416 pregnant women. |
Out of 92.06% of pregnant women who refused the H1N1 influenza vaccine, 30.28% reported lack of information about vaccination as the main reason for refusal. Of the 25 vaccinated pregnant women, 60% reported having been vaccinated on the advice of someone other than a health professional. |
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Schindler M, et al33 2012 LoE:6 MR: Level A |
- Examine Swiss pregnant women’s representations of the risks associated with seasonal flu and its vaccination in the first wave. - Sample of 29 postpartum women. |
The lack of recommendation, by health professionals, about the dangerousness of seasonal flu and the protection afforded by vaccines may have left pregnant women in a state of indecision regarding vaccination. |
| Moukarram H, et al50 2012 LoE:6 MR: Level B |
- Assess vaccine awareness and uptake among pregnant women in the local community. - Sample of 200 pregnant women. |
42.5% of pregnant women said they would take the vaccine. Regarding the main reasons for refusal, 43.5% reported concern about possible risks to the fetus and 40.9%, risk to themselves. |
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Bhaskar E, et al42 2012 LoE:6 MR: Level A |
- Identify pandemic influenza vaccination rates among pregnant women in Chennai during the first two months after influenza vaccine rollout and to analyze factors associated with vaccination. - Sample of 140 pregnant women. |
The influenza vaccination rate was 12.8%. The reasons for refusal were fear of complications (28.5%), not knowing where the vaccine was available (28.5%) and not knowing the benefits of vaccination (28.5%). |
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Kay WK, et al36 2012 LoE:6 MR: Level A |
- Estimate pH1N1 vaccination coverage among women in King County during the third trimester of pregnancy and identify sociodemographic factors, beliefs and practices associated with vaccination. - Sample of 4,205 postpartum women. |
The reasons cited by women not vaccinated against H1N1 were not being able to find a vaccination provider (20.6%) and the perception that they were not at risk of serious illness (26.1%). The reasons reported for not being vaccinated against the flu were safety issues (58%) related to the effects of the vaccine on the mother’s or fetus’ health. |
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Steelfisher GK, et al35 2011 LoE:6 MR: Level B |
- Examine drivers and barriers to pregnant women receiving the H1N1 vaccine through a national survey conducted during the pandemic. - Sample of 514 pregnant women. |
The main reason for refusing to receive the vaccine was concern about safety risks to the fetus (62%) and to herself (59%). Pregnant women who knew that the H1N1 vaccine provided protection against H1N1 flu for their babies were more likely to receive the vaccine. |
| Dlugacz Y, et al 54 2011 LoE:6 MR: Level A |
- Identify factors associated with acceptance or refusal of the 2009 H1N1 vaccination during pregnancy. - Sample of 1,325 postpartum women. |
34.2% received the 2009 H1N1 vaccine during pregnancy; 54% unvaccinated women indicated, as reason for refusal, concern about the vaccine safety for the fetus. Health professionals’ recommendation was one of the reasons for accepting the H1N1 vaccine. Of those who received the recommendation, 56% were vaccinated. |
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Goldfarb I, et al31 2011 LOE:6 MR: Level A |
- Define the uptake of H1N1 and seasonal influenza vaccination among women who delivered at an urban teaching hospital during the 2009-2010 H1N1 pandemic and explore barriers to vaccinating pregnant women. - Sample of 366 postpartum women. |
81% received H1N1 and seasonal flu vaccines. Factors for compliance were the desire to protect themselves (>60%) and their babies (>80%) and recommendation from a health professional (>60%), while refusal was motivated by media attention and recommendation from government agencies (<20%). |
| Fisher BM, et al 402011 LOE:6 MR: Level A |
- Determine influenza vaccination rates, both seasonal and H1N1 pandemic, in pregnancy during the 2009-2010 influenza season and for those women not vaccinated during pregnancy to determine reasons for non-compliance. - Sample of 813 postpartum women. |
64% of participants received vaccination against seasonal flu, and 54%, against H1N1 flu during pregnancy. Of women who did not receive both vaccines, 25% reported not being well-informed about the importance of the vaccine, 18% reported concern about the vaccine’s effects on fetal health, and 9%, about maternal health. |
| Sakaguchi S, et al 43 2010 LOE:6 MR: Level A |
- Determine how many pregnant women received the H1N1 vaccine after their call to Motherisk and explore pregnant women’s perceptions of the H1N1 vaccine and factors surrounding the decision to receive vaccination. - Sample of 130 pregnant women. |
Among pregnant women who received the vaccine, 73.1% reported concern about the risk of H1N1 infection in the fetus and/or themselves as a reason for their decision; 34.6% cited recommendations to encourage vaccination; and 3.8% mentioned a previous history of complication or illness due to influenza. Of those who did not receive the vaccine, 42.3% reported concerns about safety for themselves and/or their fetus, and 23.1% did not find the vaccine necessary. |
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Ozer A, et al46 2010 LOE:6 MR: Level A |
- Determine factors that affect pregnant women’s decisions in Turkey whether or not to be vaccinated against 2009 H1N1 influenza. - Sample of 314 pregnant women. |
The H1N1 vaccination rate was 8.9%. 75.5% of the unvaccinated thought the vaccine was harmful in the long term; 70.1% believed it could cause miscarriage, 74.2% deformity in their children and 72.3% infertility. |
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White SW, et al44 2010 LOE:6 MR: Level A |
- Audit the 2009 pandemic (H1N1) influenza vaccine acceptance in pregnant women entering the 2010 influenza season in Western Australia and identify why some women did not receive the vaccine. - Sample of 479 pregnant women. |
The H1N1 vaccination rate was 6.9%. Reasons for not vaccinating were lack of discussion or dialogue about the vaccine with health professionals during prenatal care (63.9%), concern about vaccination safety by pregnant women (61.6%) and active discouragement of prenatal vaccination (19.6%). |