Lima, Maria Amanda Correia; Cunha, Gilmara Holanda da; Galvão, Marli Teresinha Gimeniz; Rocha, Ryvanne Paulino; Franco, Kátia Barbosa; Fontenele, Marina Soares Monteiro

doi:10.1590/0034-7167-2016-0416

person Maria Amanda Correia Lima

schoolUniversidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

person Gilmara Holanda da Cunha

schoolUniversidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.schoolUniversidade Federal do Ceará, Department of Nursing, Research Group and Center of Studies on HIV/AIDS and Associated Diseases. Fortaleza, Ceará, Brazil.

person Marli Teresinha Gimeniz Galvão

schoolUniversidade Federal do Ceará, Department of Nursing, Research Group and Center of Studies on HIV/AIDS and Associated Diseases. Fortaleza, Ceará, Brazil.

person Ryvanne Paulino Rocha

schoolUniversidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

person Kátia Barbosa Franco

schoolUniversidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

person Marina Soares Monteiro Fontenele

schoolUniversidade Federal do Ceará, Department of Nursing, Health Care Research Group on HIV/AIDS and Chronic Conditions. Fortaleza, Ceará, Brazil.

CORRESPONDING AUTHOR Gilmara Holanda da Cunha E-mail:
gilmaraholandaufc@yahoo.com.br

Title	Year/ Country	Study outline/number of patients	Intervention	Outcome
Prevalence and patient awareness of medical comorbidities in an urban AIDS clinic⁽¹⁸⁾	United States 2010	Cross-sectional n = 200	Interview with use of a form	Prevalence of SAH on 27.5% black people.
Chronic illness burden and quality of life in an aging HIV population⁽¹⁹⁾	United States 2013	Cross-sectional n = 452	Interview on the phone	Prevalence of SAH on 46% people aged 50 or older.
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS⁽¹⁰⁾	Brazil 2010	Case control n = 958	Observing groups Case: patients with AP (Arterial Pressure) > 140/90 mmHg, at least on two occasions, or previous diagnosis of hypertension. Control: patients with normal AP	Prevalence of SAH in 25.6% people followed up in the clinic.
Risco cardiovascular: marcadores antropométricos, clínicos e dietéticos em indivíduos infectados pelo vírus HIV⁽¹¹⁾	Brazil 2011	Cross-sectional n = 100	Interview and physical examination	Prevalence of SAH in 35% people followed up in the clinic.
What should we know about metabolic syndrome and lipodystrophy in AIDS⁽¹²⁾	Brazil 2011	Cross-sectional n = 819	Interview and physical examination	Prevalence of SAH in 16.7% people followed up in the clinic.
Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life⁽¹⁴⁾	Brazil 2013	Cross-sectional n = 2.307	Medical Record	Prevalence of SAH in 11.9% people followed up in the clinic.
Risk of coronary artery disease in individuals infected with human immunodeficiency virus⁽¹⁵⁾	Brazil 2011	Cross-sectional n = 40		Prevalence of SAH in 55% people followed up in the clinic.
Correlates of hypertension in patients with AIDS in the era of highly-active antiretroviral therapy⁽²⁰⁾	United States 2013	Prospective cohort n = 2390	Interview, medical record and examinations	Prevalence of SAH on 22% and incidence in 64.1/1000.
Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients. A prospective study in a cohort of naive patients⁽²³⁾	Spain 2006	Prospective cohort n = 95	Interview and physical examination	Before ART†, 7% patients had SAH; After 48 weeks of ART, 26% were with high AP‡.
Lipid profile, cardiovascular risk factors and metabolic syndrome in a group of AIDS patients⁽¹³⁾	Brazil 2008	Cross-sectional n = 252	Interview and physical examination	In use of ART: 19.9% patients had SAH; No use of ART: 13.3% had SAH.
Prevalence of hypertension in HIV/AIDS patients on highly active antiretroviral therapy (haart) compared with haart naïve patients at the limbe regional hospital, Cameroon⁽²⁵⁾	Cameroon 2016	Cross-sectional n = 200	Interview and physical examination	In use of ART: 38% patients had SAH; No use of ART: 19% had SAH.

Title	Year/ Country	Study outline/ number of patients	Intervention	Outcome
Risk factors related to hypertension among patients in a cohort living with HIV/AIDS⁽¹⁰⁾	Brazil 2010	Case control n = 958	Observing groups Case: patients with AP > 140/90 mmHg, at least on two occasions, or previous diagnosis of hypertension. Control: patients with normal AP	– Advanced age – Longest time of anti-HIV positive serology – Use of ART: – SAH † family history – Low CD4+ T lymphocytes – Sedentariness: – BMI ‡ > 25 kg/m – High Waist Circumference – Triglycerides > 150 mg/dL – Blood Glucose > 100 mg/dL – Cholesterol > 200 mg/dL
What should we know about metabolic syndrome and lipodystrophy in AIDS?⁽¹²⁾	Brazil 2011	Cross-sectional n = 819	Interview and physical examination	– Advanced age – Longest time of anti-HIV positive serology – Use of ART: – High CD4+ T lymphocytes – BMI ‡ > 25 kg/m
Aging with HIV: an overview of an urban cohort in Rio de Janeiro (Brazil) across decades of life⁽¹⁴⁾	Brazil 2013	Cross-sectional n = 2307	Analysis on medical records	– Advanced age
Hospitalizations for cardiovascular disease in african americans and whites with HIV/AIDS⁽¹⁶⁾	United States 2013	Retrospective cohort n = 288	Medical records analysis	– Advanced age – Black – Women – Chronic Kidney Disease
Chronic illness burden and quality of life in an aging HIV population⁽¹⁹⁾	United States 2013	Cross-sectional n = 452	Interview on the phone	– Advanced age – Stress and depression – Low social and mental activity
Correlates of hypertension in patients with AIDS in the era of highly-active antiretroviral therapy⁽²⁰⁾	United States 2013	Retrospective cohort n = 2390	Interview, medical records analysis and examinations	– Advanced age – Black – Diabetes Mellitus – Low educational level – High weight – Triglycerides > 150 mg/dL
Hipertensión arterial, infección por el virus de la inmunodeficiencia humana y tratamiento antirretrovírico de gran actividad⁽²¹⁾	Spain 2010	Integrative review	Search on MEDLINE database	– Advanced age – Men – Low pre-treatment systolic pressure with ART – Low CD4+ T lymphocytes – Chronic kidney disease – Lipodystrophy – High Waist Circumference – Triglycerides > 150 mg/dL – Cholesterol > 200 mg/dL
Impact of highly active antiretroviral therapy on blood pressure in HIV-infected patients. A prospective study in a cohort of naive patients⁽²³⁾	Spain 2006	Retrospective cohort n = 95	Interview and physical examination	– Advanced age – Low CD4+ T lymphocytes – BMI ‡ > 25 kg/m – Triglycerides > 150 mg/dL – Cholesterol > 200 mg/dL
Prevalence of hypertension in HIV/AIDS Patients on highly active antiretroviral therapy (HAART) compared with HAART naive patients at the limbe regional hospital, Cameroon⁽²⁵⁾	Cameroon 2016	Cross-sectional n = 200	Interview and physical examination	– Advanced age – Men – Use of ART:
Prevalence and patient awareness of medical comorbidities in an urban AIDS clinic⁽¹⁸⁾	United States 2010	Cross-sectional n = 200	Filling out cards, interview and medical records	– Women – Longest time of anti-HIV positive serology – Use of ART:
Cardiovascular profile and events of US adults 20-49 years with HIV: results from the NHANES 1999-2008⁽¹⁷⁾	United States 2013	Cross-sectional n = 12.339	Data analysis of the National Center for Health Statistics.	– Longest time of anti-HIV positive serology
Lipid profile, cardiovascular risk factors and metabolic syndrome in a group of AIDS patients⁽¹³⁾	Brazil 2008	Cross-sectional n = 252	Interview and physical examination	– Diabetes Mellitus – Arteriosclerosis – Smoking
Risco cardiovascular: marcadores antropométricos, clínicos e dietéticos em indivíduos infectados pelo vírus HIV⁽¹¹⁾	Brazil 2011	Cross-sectional n = 100	Interview and physical examination	– Smoking – Blood Glucose > 100 mg/dL – Cholesterol > 200 mg/dL – Low values of high density lipoproteins

Title	Year/ Country	Study outline/ number of patients	Intervention	Outcome
Hipertensión arterial en pacientes infectados por el virus de la inmunodeficiencia humana⁽²²⁾	Spain 2013	Integrative review	Search in database	– Protease inhibitors (ritonavir, indinavir, saquinavir, lopinavir, nelfinavir and amprenavir): Increase of AP* and potentialization or decrease of the effect of calcium channel blockers. – Nevirapine: Interaction with calcium channel blockers – Delavirdine: Increases plasmatic levels of antihypertensive medicines
Cardiovascular manifestations of HIV infection⁽²⁴⁾	Italy 2001	Integrative review	Search in database	– Protease inhibitors (ritonavir, indinavir, saquinavir, lopinavir, nelfinavir and amprenavir): Coronary artery disease, lipodystrophy, insulin resistance, high cholesterol, high triglycerides and infarction.
Una década de terapia anti-retroviral: perfil de pacientes con 10 años de triterapia de alta efectividad⁽²⁶⁾	Chile 2012	Retrospective cohort	Medical records analysis	– Lipodystrophy – High triglycerides

[TFN1] Nota: *HAS: Hipertensão arterial sistêmica;

[TFN2] ^†
TARV: Terapia antirretroviral;

[TFN3] ^‡
PA: Pressão arterial.

Hipertensión arterial sistémica en personas que viven con VIH/Sida: revisión integradora