Immunological aspects of unrelated bone marrow transplantation: alloreactivity and immunoreconstitution

Aspectos imunológicos do transplante de medula óssea não relacionado: aloreatividae e imunoreconstituição

Abstract

The main complications after bone marrow transplantation (BMT) are graft versus host disease (GvHD), post-transplant viral infections and disease relapse. The underlying causes of these problems are the degree of HLA matching between donor and patient and the rate of immune reconstitution.

Bone marrow transplantations; HLA matching; alloreativity; immune reconstrution