schoolMD, FRCPC. Department of Medicine, Behavioural Neurology Division, University of Toronto, Toronto, ON, Canada, M5S 1A8. St Michael’s Hospital Memory Disorders Clinic, St. Michael’s Hospital, Toronto, ON, Canada, M5S 1A8. Faculty of Medicine, Department of Psychiatry, University of Toronto, Canada, M5S 1A8.University of TorontoCanadaToronto, ON, CanadaMD, FRCPC. Department of Medicine, Behavioural Neurology Division, University of Toronto, Toronto, ON, Canada, M5S 1A8. St Michael’s Hospital Memory Disorders Clinic, St. Michael’s Hospital, Toronto, ON, Canada, M5S 1A8. Faculty of Medicine, Department of Psychiatry, University of Toronto, Canada, M5S 1A8.schoolSt. Michael’s Hospital, St Michael’s Hospital Memory Disorders Clinic, Toronto, ON, CanadaSt. Michael’s HospitalCanadaToronto, ON, CanadaSt. Michael’s Hospital, St Michael’s Hospital Memory Disorders Clinic, Toronto, ON, CanadaschoolUniversity of Toronto, Faculty of Medicine, Department of Psychiatry, CanadaUniversity of TorontoCanadaCanadaUniversity of Toronto, Faculty of Medicine, Department of Psychiatry, Canada
person Melissa Leggieri
schoolBSc. Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8. Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada, M5S 1A8.St. Michael’s HospitalCanadaToronto, ON, CanadaBSc. Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8. Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada, M5S 1A8.schoolUniversity of Toronto, Institute of Medical Sciences, Toronto, ON, CanadaUniversity of TorontoCanadaToronto, ON, CanadaUniversity of Toronto, Institute of Medical Sciences, Toronto, ON, Canada
person Tom A. Schweizer
schoolPhD. Department of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, Canada, M5S 1A8. Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8.University of TorontoCanadaToronto, ON, CanadaPhD. Department of Surgery, Division of Neurosurgery, University of Toronto, Toronto, ON, Canada, M5S 1A8. Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8.schoolSt. Michael’s Hospital, Li Ka Shing Knowledge Institute, Keenan Research Centre for Biomedical Research, Toronto, ON, CanadaSt. Michael’s HospitalCanadaToronto, ON, CanadaSt. Michael’s Hospital, Li Ka Shing Knowledge Institute, Keenan Research Centre for Biomedical Research, Toronto, ON, Canada
person Raul L. Arizaga
schoolMD. Faculty of Medicine, University of Buenos Aires, Viamonte 430, 1053 Buenos Aires, Argentina.University of Buenos AiresArgentinaBuenos Aires, ArgentinaMD. Faculty of Medicine, University of Buenos Aires, Viamonte 430, 1053 Buenos Aires, Argentina.
person Ricardo F. Allegri
schoolMD. Centro de Memoria y Envejecimiento. Ins Investigaciones Neurol “Raul Carrea” (FLENI) Buenos Aires, Argentina. Neurosciencias. Universidad de la Costa (CUC). Colombia.Ins Investigaciones Neurol “Raul Carrea”ArgentinaBuenos Aires, ArgentinaMD. Centro de Memoria y Envejecimiento. Ins Investigaciones Neurol “Raul Carrea” (FLENI) Buenos Aires, Argentina. Neurosciencias. Universidad de la Costa (CUC). Colombia.schoolUniversidad de la Costa, Neurosciencias, ColombiaUniversidad de la CostaColombiaColombiaUniversidad de la Costa, Neurosciencias, Colombia
person Corinne E. Fischer
schoolMD, FRCPC. St Michael’s Hospital Memory Disorders Clinic, St. Michael’s Hospital, Toronto, ON, Canada, M5S 1A8. Faculty of Medicine, Department of Psychiatry, University of Toronto, Canada, M5S 1A8. Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8.St. Michael’s HospitalCanadaToronto, ON, CanadaMD, FRCPC. St Michael’s Hospital Memory Disorders Clinic, St. Michael’s Hospital, Toronto, ON, Canada, M5S 1A8. Faculty of Medicine, Department of Psychiatry, University of Toronto, Canada, M5S 1A8. Keenan Research Centre for Biomedical Research, Li Ka Shing Knowledge Institute, St. Michael’s Hospital, 209 Victoria Street, Toronto, ON, Canada M5B 1T8.schoolUniversity of Toronto, Faculty of Medicine, Department of Psychiatry, Toronto, CanadaUniversity of TorontoCanadaToronto, CanadaUniversity of Toronto, Faculty of Medicine, Department of Psychiatry, Toronto, CanadaschoolSt. Michael’s Hospital, Li Ka Shing Knowledge Institute, Keenan Research Centre for Biomedical Research, Toronto, ON, CanadaSt. Michael’s HospitalCanadaToronto, ON, CanadaSt. Michael’s Hospital, Li Ka Shing Knowledge Institute, Keenan Research Centre for Biomedical Research, Toronto, ON, Canada
Disclosure: The authors report no conflicts of interest.
Author contributions. Luis Fornazzari: discussed the idea, reviewed the original classical publications, reviewed recent contemporary papers and prepared the final manuscript. Melissa Leggieri: discussed the idea, reviewed the original classical publications, reviewed recent contemporary papers and prepared the final manuscript. Tom A Schweizer: reviewed recent contemporary papers and reviewed the final manuscript. Raul L Arigaza: discussed the idea, reviewed the original classical publications, and reviewed the final manuscript. Ricardo F Allegri: discussed the idea, reviewed the original classical publications, and reviewed the final manuscript. Corinne E Fischer: reviewed recent contemporary papers and reviewed the final manuscript.