BREAST CANCER AND ANALYSIS OF THE FACTORS RELATED TO THE DISEASE DETECTION AND STAGING METHODS

Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work - Santos CMF dos, Santana VM de, Gomes TN, Cavalcante LTS; Drafting the work or revising it critically for important intellectual content - Santos CMF dos, Santana VM de, Gomes TN, Cavalcante LTS, Lima MCL de; Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved - CAR de O. All authors approved the final version of the text

Corresponding author: Morgana Cristina Leôncio de Lima, Universidade de Pernambuco - Recife, PE, Brasil, E-mail:
morgana_delima@hotmail.com

Associate editor: Luciana de Alcântara Nogueira

Factor assessed	n (350)	%	p-valor*
Age
<50 years old	141	40,3	0,085
50-69 years old	172	49,1
≥70 years old	37	10,6
Minimum - Maximum	26-85
Mean ± Standard Deviation	53,4±11,9
Marital status
Single	112	32	<0,001
Married/Stable Union	158	45,1
Widow	52	14,9
Divorced	28	8
Income
No income	38	10,9	<0,001
<1 Minimum wage	42	12
1 Minimum wage	196	56
>1 Minimum wage	74	21,1
Origin
Recife-PE	77	22	<0,001
Metropolitan Region of Recife-PE	95	27,1
Inland PE	176	50,3
Other state	2	0,6
Religion
Catholic	198	56,6	<0,001
Evangelical	113	32,3
Spiritist	10	2,9
Other religions	29	8,3
Occupation
Employed/Autonomous	96	27,4	0,078
Unemployed	82	23,4
Retired/Pensioner	106	30,3
Benefit	66	18,9
Schooling
No schooling	28	8	<0,001
Elementary School	156	44,6
High School	130	37,1
Higher Education/Graduate studies	36	10,3
Skin color
White	111	31,7	<0,001
Black	32	9,1
Brown	205	58,6
Asian	2	0,6

Factor assessed	n (350)	%	p-value*
Use of breast prosthesis
Yes	7	2	<0,001
No	343	98	<0,001
Use of contraceptives
Yes	192	54,9	0,069
No	158	45,1	0,069
1^st degree relatives with breast cancer
Yes	110	31,4	<0,001
No	240	68,6	<0,001
Personal history of cancer
Yes	80	22,9	<0,001
No	270	77,1	<0,001
Presence of signs and symptoms
Yes	302	86,3	<0,001
No	48	13,7	<0,001

Factor assessed	n (350)	%	p-valor*
Identification method
BSE	262	74,9	<0,001
CBM	19	5,4
US	18	5,1
MMG	51	14,6
Access to the health system
BHU physician	109	31,1	0,016
BHU nurse	30	8,6
Consultation with a specialist	118	33,7
Hospital	93	26,6
Diagnostic staging
Early stage	97	27,7	<0,001
Locally advanced	231	66
Metastatic cancer	22	6,3

Factor assessed	Breast cancer identification method								p-value
Factor assessed	BSE	n(%)	CBM	n(%)	US	n(%)	Mammography	n(%)	p-value
Age
<50 years old	115	81,6	6	4,3	10	7,1	10	7,1	0,034¹
50-69 years old	123	71,5	10	5,8	6	3,5	33	19,2
≥70 years old	24	64,9	3	8,1	2	5,4	8	21,6
Signs and symptoms
Yes	259	85,8	12	4	6	2	25	8,3	<0,001²
No	3	6,3	7	14,6	12	25	26	54,2	<0,001²
Access to the health system
BHU physician	90	82,6	5	4,6	4	3,7	10	9,2	0,003²
BHU nurse	22	73,3	6	20	1	3,3	1	3,3
Consultation with a specialist	86	72,9	6	5,1	9	7,6	17	14,4
Hospital	64	68,8	2	2,2	4	4,3	23	24,7

Factor assessed	Diagnostic staging						p-value
Factor assessed	Early stage	n(%)	Locally advanced	n(%)	Metastatic cancer	n(%)	p-value
Identification method
BSE	63	24	184	70,2	15	5,70%	0,024²
CBM	5	26,3	13	68,4	1	5,3
Routine US	8	44,4	7	38,9	3	16,7
MMG	21	41,2	27	52,9	3	5,9
Signs and symptoms
Yes	75	24,8	209	69,2	18	6	0,006¹
No	22	45,8	22	45,8	4	8,3	0,006¹
1^st degree relatives with breast cancer
Yes	41	37,3	60	54,5	9	8,2	0,009¹
No	56	23,3	171	71,3	13	5,4	0,009¹
Personal history of cancer
Yes	21	26,3	48	60	11	13,8	0,007¹
No	76	28,1	183	67,8	11	4,1	0,007¹

[TFN4] ^*
p-value obtained in the X² test for comparison of proportions.

[2] Source: The authors (2019).