Initial experience with ocriplasmin in the treatment of vitreomacular traction

Garcia, José Maurício Botto de Barros; Isaac, David Leonardo Cruvinel; Ávila, Marcos

doi:10.5935/0004-2749.20160026

Tabla de contenido Anterior Actual Siguiente

Tabla de contenido

Original Articles • Arq. Bras. Oftalmol. 79 (02) • Mar-Apr 2016 • https://doi.org/10.5935/0004-2749.20160026 linkcopy

Initial experience with ocriplasmin in the treatment of vitreomacular traction

Experiência inicial com ocriplasmina no tratamento da tração vitreorretiniana

Authorship SCIMAGO INSTITUTIONS RANKINGS

This study aimed to report the clinical and structural outcomes of intravitreal ocriplasmin in the treatment of vitreomacular interface disorders in two tertiary centers in Brazil. A retrospective study was performed by reviewing medical records and spectral domain optical coherence tomography (SD-OCT) findings of seven patients who were treated with a single ocriplasmin injection. A total of 57.14% of patients achieved resolution of vitreomacular traction as evidenced by SD-OCT. Regarding our functional results, 87.71% maintained or improved visual acuity after follow-up. To the best of our knowledge, this is the first study reporting initial results of ocriplasmin therapy in Brazil.

Keywords:
Vitreous body/pathology; Fibrinolytic agents/therapeutic use; Fibrinolysin/therapeutic use; Tomography, optical coherence; Tertiary care centers

Patient	Sex	Age	Eye	Lens status	ERM	MH	Focal VMT	Broad VMT	Initial BCVA (logMAR)	Final BCVA (logMAR)	Initial BCVA (Snellen)	Final BCVA (Snellen)	Follow up in days	VMT resolution (SD-OCT)
1	F	49	OS	Phakic	–	–	+	–	0.30	0.18	20/40	20/30	28	+
2	F	74	OD	PCIOL	–	–	+	–	0.10	0.00	20/25	20/20	4	+
3	F	62	OD	PCIOL	–	–	+	–	0.18	0.00	20/30	20/20	40	+
4	F	79	OS	PCIOL	–	–	+	–	0.30	0.30	20/40	20/40	61	–
5	F	63	OS	PCIOL	–	–	+	–	0.00	0.40	20/20	20/50	28	–
6	M	72	OD	PCIOL	–	–	–	+	0.30	0.18	20/40	20/30	319	–
7	F	64	OS	PCIOL	–	–	+	–	0.18	0.18	20/30	20/30	14	+

location_on

Conselho Brasileiro de Oftalmologia Rua Casa do Ator, 1117 - cj.21, 04546-004 São Paulo SP Brazil, Tel: 55 11 - 3266-4000, Fax: 55 11- 3171-0953 - São Paulo - SP - Brazil
E-mail: abo@cbo.com.br

rss_feed Acompañe los números de esta revista en su lector de RSS

[TFN01] PCIOL: posterior chamber intra ocular lens; logMAR: logarithm of minimum angle of resolution; OD: right eye; OS: left eye; ERM: epiretinal membrane; MH: macular hole; VMA: vitreomacular adhesion; VMT: vitreomacular traction; SD-OCT: spectral domain optical coherence tomography.